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Mysterious Borg DNA Can Copy Genes From Other Cells!

By: Jason Goodyer
Originally Published in  
Science Focus
Many round cells growing on a surface
© Getty
Vocabulary

Genetic entity (noun): A DNA-based structure with genetic material but not considered a full organism.

Archaea (noun): Ancient, single-celled organisms distinct from bacteria and eukaryotes.

Eukaryotic (adjective): Describing a cell that has a nucleus and other specialized structures (called organelles) enclosed within membranes.

Palindromic (adjective): Reading the same forward and backward, often used in relationship to words, numbers, or sequences.

Plasmid (noun): A small DNA molecule separate from the main genetic material of a cell.

In a discovery that sounds like science fiction, researchers have found mysterious DNA strands called Borgs. These strange genetic entities might hold the key to fighting climate change and revolutionizing gene editing alongside CRISPR technology.

Meet the Borg: a DNA discovery from mud

In a muddy wetland pool, researchers from UC Berkeley uncovered enigmatic DNA structures they named "Borgs." Inspired by the Star Trek species that assimilates the abilities of others, Borgs possess a remarkable talent — they absorb genes from their host cells. These hosts are archaea, ancient single-celled organisms believed to be the ancestors of eukaryotic life.

Tiny helpers fighting climate change

Borgs play an intriguing role in methane-eating microbes. Methane, a potent greenhouse gas, significantly contributes to global warming. Some microbes consume methane, but those with Borgs have enhanced metabolic capabilities, allowing them to break down methane even more efficiently. This makes them promising candidates for reducing emissions in agriculture and wetlands.

Like CRISPR, but maybe better!

Even more exciting is the potential for Borgs to enhance gene editing. CRISPR, short for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary tool that allows scientists to cut and modify DNA sequences. It has transformed medicine and agriculture by enabling precise genetic changes. Borgs, with their unique genetic content, might reveal new systems for manipulating DNA, potentially expanding CRISPR-like technologies.

So, what's next?

The next phase of research will focus on determining whether Borgs permanently exist in host cells (like plasmids) or behave more like viruses, entering and leaving cells. Additionally, scientists plan to explore whether Borgs could be used to reduce methane emissions in rice paddies and wetlands, offering new strategies for combating climate change.

The discovery of Borgs highlights how much untapped potential lies within the microbial world, with the power to shape both science and the planet’s future.

© Jason Goodyer / Our Media